BOSTON–(BUSINESS WIRE)–December 21, 2020 — Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced the U.S. Food and Drug Administration (FDA) expanded
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Noncoding mutations contribute to autism risk
A whole-genome sequencing study of nearly 2,000 families has implicated mutations in ‘promoter regions’ of the genome—regions that precede the
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Variation in cancer-causing KRAS mutations greater than thought
The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a
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Same mutations underpin spread of cancer in individuals, study finds
Scientists have arrived at a key understanding about how cancers in individual patients spread, or metastasize, a study from the
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New study explains why genetic mutations cause disease in some people but not in others
Researchers at the New York Genome Center (NYGC) and Columbia University have uncovered a molecular mechanism behind one of biology’s
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AI accurately predicts effects of genetic mutations in biological dark matter
A new machine learning framework, dubbed ExPecto, can predict the effects of genetic mutations in the so-called “dark matter” regions
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Looking beyond mutations, researchers take a new approach to an old oncogene
KRAS is one of the most commonly mutated and widely studied genes in cancer; a quick PubMed search for KRAS
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Males with BRCA mutations have increased risk of certain cancers
(HealthDay)—Males with BRCA mutations have increased incidence of malignant disease, specifically prostate, melanoma, pancreas, and breast cancers, according to a
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