Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene
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Single-cell analysis reveals how melanoma cells resist immunotherapy
Unleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable outcomes in some cancer patients, but
Continue reading »New data confirm antioxidants accelerate spread of malignant melanoma
Now there is additional evidence of the connection between the intake of antioxidant supplements and increased tumor growth. Experiments on
Continue reading »Researchers discover epigenetic reason for drug resistance in a deadly melanoma
Mount Sinai researchers have discovered a previously unknown reason for drug resistance in a common subtype of melanoma, one of
Continue reading »Retinoic acid may improve immune response against melanoma
Immunotherapies use the immune system to fight cancer. But cancers like melanoma have found ways to turn off the immune
Continue reading »New guidelines increase melanoma staging reproducibility
(HealthDay)—Greater reproducibility and higher concordance are seen for melanoma staging with the American Joint Committee on Cancer (AJCC) classification of
Continue reading »Lymphatic endothelial cells promote melanoma to spread
The lymph vessel endothelial cells play an active role in the spread of melanoma, according to the new study conducted
Continue reading »PAs may have lower diagnostic accuracy for melanoma
(HealthDay)—Physician assistants (PAs) perform more skin biopsies per case of skin cancer diagnosed and diagnose fewer melanomas in situ than
Continue reading »TLR9 agonist CMP-001-pembrolizumab combination shows early efficacy for metastatic melanoma resistant to anti-PD-1
A combination of CMP-001, an intratumoral Toll-like receptor 9 (TLR9) agonist, and pembrolizumab (Keytruda), tested in patients with metastatic melanoma
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