Among women who identified as Black/African American or Hispanic/Latina, those with low blood levels of vitamin D were more likely to develop breast cancer than those with adequate levels. In the study published by Wiley online in Cancer, a peer-reviewed journal of the American Cancer Society, the link between low vitamin D and breast cancer was particularly evident among Hispanic/Latina women.
Black/African American or Hispanic/Latina have lower average vitamin D levels than non-Hispanic white women. Although research suggests that vitamin D may protect against breast cancer, few studies have considered the role of race/ethnicity in this link.
To investigate, Katie O’Brien, Ph.D., of the National Institute of Environmental Health Sciences, and her colleagues collected blood samples from 415 women (290 Black/African American, 125 non-Black Hispanic/Latina) who later developed breast cancer, as well as from 1,447 women (1,010 Black/African American, 437 Hispanic/Latina) who did not develop breast cancer.
Over an average follow-up of 9.2 years, women with sufficient vitamin D levels had a 21% lower breast cancer rate than women with vitamin D deficiency (<20 ng/mL). The link was strongest among Hispanic/Latina women, who had a 48% lower rate if they had sufficient vitamin D levels. The link was weaker among Black/African American women, who had an 11% lower rate if they had sufficient vitamin D.
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